Figure 7.

Effect of germ cells on claudin 5 expression. Representative images from W/W^v mice that received spermatogonial stem cell transplants from wild-type donors showing (a) expression of claudin 5 in tubules in which spermatogenesis was established; scale bar, 50 µm; (b) mixture of spermatogenic and aspermic tubules (PAS/hematoxylin); scale bar, 100 µm; (c) absence of claudin 5 in aspermic tubules; scale bar, 75 µm. Claudin 5 is also expressed in the vascular endothelium. (Note: the images are from different mice; modified from Morrow et al. (2009).)