Table 1.
Behavior | Experimental Groups | |||
---|---|---|---|---|
SAL-SAL | SAL-AMPH | AMPH-SAL | AMPH-AMPH | |
Total distance traveled (Horizontal activity) | 4107 ± 765 | 16812 ± 4046* | 3956 ± 499 | 26597 ± 3363** ˆ |
Vertical activity (Rearing) | 402 ± 125 | 1730 ± 569* | 373 ± 94 | 3073 ± 594** ˆ |
Behavioral data are expressed as total distance traveled (cm) or vertical activity (beam breaks) measured over 3h following the SAL or AMPH (1 mg/kg i.p.) challenge administered to rats pretreated with repeated SAL or AMPH. Mean (± SEM), n = 6-8,
p<0.05,
p<0.01 vs. SAL-SAL,
p<0.05 vs. SAL-AMPH. SAL, saline; AMPH, amphetamine