Table 2.

Median Levels and Interquartile Range (IQR) of Biomarkers for SMART, CARDIA and MESA Participants

	Participants aged 33–44 years					Participants aged 45–76 years
	SMART (N=287*)		CARDIA (N=3231†)		% Diff.‡ (P-value)	SMART (N=494§)		MESA (N=5386)		% Diff.‡ (P-value)
	Median	IQR	Median	IQR		Median	IQR	Median	IQR
hsCRP (μg/mL)	2.12	0.80–4.77	1.36	0.53–3.78	55.2 (<0.001)	2.68	1.07–6.01	2.17	0.94–4.70	49.6 (<0.001)
IL-6 (pg/mL)	2.09	1.26–3.49	1.29	0.80–2.07	62.1 (<0.001)	2.63	1.63–4.18	1.23	0.79–1.92	151.6 (<0.001)
D-dimer (μg/mL)	0.29	0.17–0.55	NA	NA	NA	0.34	0.20–0.61	0.20	0.13–0.35	94.3 (<0.001)
Cystatin C (mg/dl)	0.94	0.82–1.07	NA	NA	NA	1.00	0.88–1.17	0.85	0.76–0.96	27.2 (<0.001)

NA = not available

^*172 had cystatin C measurements.

^†689 had IL-6 measurements.

^‡% difference in means of log transformed value, adjusted for age, race, gender, BMI, smoking, total/HDL cholesterol, diabetes, lipid-lowering therapy and blood pressure lowering therapy.

^§231 had cystatin C measurements.