Table 1.
Human Cancer Cell Line and Murine P-388 Lymphocytic Inhibitory Activities. P388 Murine Lymphoceutic Leukemia and Human Cancer Cell Results [μg/mL] (ED 50)
Compound | leukemia | pancreas | breast | CNS | lung-NSC | colon | prostate | leukemia | neuroblastoma |
---|---|---|---|---|---|---|---|---|---|
P388 | BxPC-3 | MCF-7 | SF-268 | NCI-H460 | KM20L2 | DU-145 | Jurkat | Shsy5y | |
2 | 0.039 | 0.028 | 0.032 | 0.017 | 0.048 | 0.062 | 0.016 | 0.163 | 0.163 |
3 | 0.44 | – | – | – | 0.29 | 0.22 | – | – | – |
4 | 0.001 | 0.026 | 0.019 | 0.021 | 0.032 | 0.021 | 0.011 | – | – |
7 | 0.029 | 0.046 | 0.034 | 0.059 | 0.043 | 0.051 | 0.040 | – | – |
51 | 0.0016 | 0.0019 | 0.00031 | 0.00055 | 0.0001 | 0.00037 | 0.00021 | ||
52 | 0.061 | 0.25 | 0.041 | 0.17 | 0.029 | 0.13 | 0.13 | ||
45 | 0.19 | 0.65 | 0.09 | 0.26 | 1.615 | 1.615 | |||
46 | 0.11 | 0.29 | 0.11 | 0.37 | 0.183 | 0.183 |