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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Pediatr Clin North Am. 2010 Feb;57(1):297–322. doi: 10.1016/j.pcl.2009.11.003

Table 1.

cGVHD Risk Factors

Patient Donor/Graft Transplant
Increased cGVHD risk Older age
Malignancy
Female donor to male patient
Mismatched
Unrelated
Peripheral Blood Stem Cells
Donor Lymphocyte Infusions
Older age
Acute GVHD
Total Body Irradiation in preparative regimen
Possible increased cGVHD risk CMV positive
CMV reactivation
CD 34+ cell dose

Decreased cGVHD risk Younger age Cord blood Anti-thyroglobulin in preparative regimen
Campath-1H in preparative regimen
Possible decreased cGVHD risk Methotrexate and cyclosporine prophylaxis