Table 1.

Demographic and Clinical Characteristics of the Sample

Demographic and clinical characteristics	Comparison subjects (N = 32), Mean (SD); (Range) or N (%)	Depressed subjects (N = 71), Mean (SD); (Range) or N (%)	Testing differences between groups
Current age (years)	71.0 (6.7); [56.3–89.5]	72.2 (6.2); [60.3–91.7]	t-value = −0.93, DF = 101 P-value = 0.36
Men, N (%)	15 (46.9%)	22 (31.0%)	Fisher’s exact test, P-value = 0.13
Caucasian, N (%)	28 (87.5%)	65 (91.6%)	Fisher’s exact test P-value = 0.50
Education, years	14.9 (2.4); [12–20]	14.0 (2.7); [8–20]	t-value = 1.50, DF = 101 P-value = 0.14
Folstein mini mental state examination	29.0 (1.0); [26–30]	28.7 (1.5); [24–30]	t-valuea= 1.27, DFa = 86.2 P-value = 0.21
Hamilton Rating Scale for depression, 17 item	2.4 (1.8), (N = 31); [0–6]	18.3 (3.0); [15–25]	t-valuea= —32.59, DFa = 89.4 P-value < 0.0001
Mattis Dementia Rating Scale	139.6 (2.9); [133–144]	137.4 (4.4); [125–144]	t-valuea = 3.01, DFa = 88 P-value = 0.003
EXIT	6.7 (3.6), (N = 31); [0–14]	7.9 (3.5); [0–17]	t-value = − 1.55, DF = 100 P-value = 0.12
Total duration of depression (years)		19.9 (19.2)
Duration of current episode of depression (weeks)	—	120.4 (173.7), (N = 70); [3–1040]	—
Proportion of subjects with early onset depression (age of onset <60)	—	38 (53.5%)
Proportion of subjects with recurrent depression (number of episodes of depression ⩾2)	—	43 (60.6%)
Age of onset of first episode of depression	—	52.3 (20.1); [10–87]	—
Proportion of subjects receiving antidepressants at baseline	—	12 (17.1%)	—
Proportion of subjects receiving antipsychotics at baseline	—	1 (1.4%)	—
Proportion of subjects receiving benzodiazepines at baseline	1 (3.1%)	19 (27.1%)	Fisher exact P-value = 0.003

^aSatterthwaite method for unequal variance.