Table 3.

Correlation of ROIs Volumes with Age of Onset and Total Duration of Depressive Illness

	Correlation with age of onset		Correlation with duration of depression
ROI	Pearson correlation coefficient	P-value	Pearson correlation coefficient	P-value
Frontal superior area	−0.27	0.023	0.16	0.196
Frontal superior orbital area	−0.22	0.060	0.16	0.173
Frontal middle area	−0.24	0.047	0.15	0.201
Frontal orbital areaa	−0.27	0.022	0.17	0.151
Frontal inferior areab	−0.18	0.129	0.06	0.593
Frontal medial superior area	−0.33	0.005	0.19	0.104
Rectus	−0.08	0.519	−0.02	0.868
Insula	−0.16	0.172	0.07	0.588
Cingulumc	−0.27	0.023	0.19	0.115
Cingulum Posterior Area	0.12	0.310	−0.11	0.371
Hippocampus	−0.17	0.169	0.07	0.549
Parahippocampal area	−0.31	0.010	0.25	0.038
Amygdala	−0.16	0.189	0.08	0.524
Parietal superior area	−0.12	0.320	0.04	0.763
Parietal inferior area	−0.37	0.001	0.26	0.030
Precuneus	−0.22	0.069	0.16	0.179
caudate	−0.15	0.224	0.23	0.056
Putamen	−0.24	0.044	0.19	0.116
Pallidum	−0.14	0.243	0.10	0.393
Thalamus	−0.23	0.057	0.13	0.293
Temporal superior area	−0.19	0.112	0.01	0.916
Temporal poled	−0.24	0.042	0.09	0.457
Temporal middle area	−0.28	0.018	0.12	0.337
Temporal inferior area	−0.24	0.048	0.08	0.513

^aFrontal lateral orbital+frontal inferior orbital+frontal middle orbital.

^bFrontal inferior operculum+frontal inferior_Tri.

^cCingulum anterior+cingulum middle.

^dTemporal pole superior+temporal pole middle.