Table 1.

Respondents’ Beliefs about the Purpose of the Clinical Trial and Their Decision Regarding Participation

	N	Computer-Based Tool %	NCI Pamphlet %	Total %	p-value
What do you think is the purpose of the investigational study?
To see if the drug works	122	57.8	56.9	57.4	0.919
To see if the drug is safe	115	34.4	16.7	26.1	0.030^a
To figure out the best dosage	115	29.0	15.1	22.6	0.075
To see if the drug will help me	119	25.0	29.1	26.9	0.616
To cure my cancer	118	17.2	13.0	15.3	0.525
Why do you think the physician talked to you about joining the study?
I might benefit from the drug	116	46.8	25.9	37.1	0.020^a
I don’t have any other standard treatment options	113	24.6	17.3	21.2	0.345
I am a good candidate for the trial	112	21.7	26.9	24.1	0.517
S/he thought I might be willing to help	113	3.3	11.3	7.1	0.144
Other drugs had stopped working	113	13.1	21.2	16.8	0.255
Did you feel like you had the option to refuse to be in the investigational study?
Yes	119	95.6	93.1	94.4
No	7	4.4	6.9	5.6	0.544
Did you decide to enroll in the current study?
Yes	84	78.3	74.0	76.4
No	26	21.7	26.0	23.6	0.594

p < 0.05

Note: Some variables may add up to greater than 100% as respondents could choose all options that apply.