Table 2.
Respondents’ Perception of the Benefits and Side Effects of the Investigational Study to Both Themselves and Other Cancer Patients
| N | Computer-Based Tool % | NCI Pamphlet % | Total % | p-value | |
|---|---|---|---|---|---|
| Perceived Benefits and Side Effects of Investigational Study for Other Cancer Patients | |||||
| Most cancer patients who enroll in investigational studies like the one presented to you: | |||||
| Have cancer get worse/experience no change in their cancer | 13.2 | 6.8 | 10.2 | ||
| Experience some short-term improvement in their cancer | 127 | 35.3 | 40.7 | 37.8 | |
| Experience long-term improvement/complete cure | 10.3 | 11.9 | 11.0 | ||
| Don’t know | 41.2 | 40.7 | 40.9 | 0.659 | |
| Most cancer patients who enroll in investigational studies like the one presented to you experience: | |||||
| No side effects | 4.5 | 0.0 | 2.4 | ||
| Minor side effects | 126 | 65.7 | 72.9 | 69.0 | |
| Major side effects | 7.5 | 6.8 | 7.1 | ||
| Don’t know | 22.4 | 20.3 | 21.4 | 0.398 | |
| Perceived Benefits and Side Effects of Investigational Study for Respondents Themselves | |||||
| While participating in the investigational study, do you expect: | |||||
| For those who decided to enroll in the clinical trial: | |||||
| To have your cancer get worse or experience no change | 4.3 | 0.0 | 2.5 | ||
| To experience some short-term improvement in your cancer | 80 | 39.1 | 32.4 | 36.3 | |
| To experience some long-term improvement or cure | 41.3 | 61.8 | 50.0 | ||
| Don’t know | 15.2 | 5.9 | 11.3 | 0.181 | |
| For those who decided not to enroll in the trial: | |||||
| To have your cancer get worse or experience no change | 36.4 | 8.3 | 21.7 | ||
| To experience some short-term improvement in your cancer | 23 | 36.4 | 33.3 | 34.8 | |
| To experience some long-term improvement or cure | 9.1 | 16.7 | 13.0 | ||
| Don’t know | 18.2 | 41.7 | 30.4 | 0.336 | |
| While participating in the investigational study, do you expect to experience: | |||||
| For those who decided to enroll in the clinical trial: | |||||
| No side effects | 4.3 | 5.6 | 4.9 | ||
| Minor side effects | 82 | 84.8 | 88.9 | 86.6 | |
| Major side effects | 2.2 | 0.0 | 1.2 | ||
| Don’t know | 8.7 | 5.6 | 7.3 | 0.764 | |
| For those who decided not to enroll in the trial: | |||||
| No side effects | 0.0 | 0.0 | 0.0 | ||
| Minor side effects | 23 | 81.8 | 58.3 | 84.2 | |
| Major side effects | 9.1 | 16.7 | 15.8 | ||
| Don’t know | 9.1 | 25.0 | 17.4 | 0.462 | |
| Do you think joining an investigational study will have any impact on your prognosis? | |||||
| Yes | 100 | 80.8 | 85.4 | 83.0 | |
| No | 19.2 | 14.6 | 17.0 | 0.536 | |
| If yes, do you think it will have a positive or negative impact on your prognosis? | |||||
| Positive | 81 | 97.6 | 97.5 | 97.5 | |
| Negative | 2.4 | 2.5 | 2.5 | 1.000 | |