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. Author manuscript; available in PMC: 2010 May 18.
Published in final edited form as: IRB. 2009 May–Jun;31(3):1–10.

Table 3.

Participants’ Self-Reported Reasons for Deciding to Participate in an Investigational Study

Computer-Based Tool % NCI Pamphlet % Total % p-value
How much did the following reasons contribute to your decision to join an investigational study?
 Contributed a lot 100.0 94.6 97.6
 Contributed a little/did not contribute 0.0 5.4 2.4 0.191
Joining the investigational study gave me hope.
 Contributed a lot 87.0 94.6 90.4
 Contributed a little/did not contribute 13.0 5.4 9.6 0.289
I trust the physician who presented the study to me.
 Contributed a lot 91.5 88.9 90.4
 Contributed a little/did not contribute 8.5 11.1 9.6 0.722
Because it might help me fight my cancer.
 Contributed a lot 93.6 83.8 89.3
 Contributed a little/did not contribute 6.4 16.2 10.7 0.173
The investigational study gave me the best chance medically.
 Contributed a lot 84.8 83.3 84.1
 Contributed a little/did not contribute 15.2 16.7 15.9 0.858
The investigational study was a way to help others.
 Contributed a lot 71.7 64.9 68.7
 Contributed a little/did not contribute 28.3 35.1 31.3 0.502
The physician who presented the investigational study thought it would be a good idea to join.
 Contributed a lot 70.2 48.6 60.7
 Contributed a little/did not contribute 29.8 51.4 39.3 0.045

Note: These questions were only asked of the 76% of participants who decided to participate in an investigational study.