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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Int J Dermatol. 2010 Mar;49(3):239–248. doi: 10.1111/j.1365-4632.2009.04322.x

Table 1.

Bisphosphonates: Dosing, administration

Drug Name Dosing: Prevention Dosing: Treatment

Alendronate 5 mg/day (oral) 5 or 10 mg/day (oral)
35 mg once weekly (oral) 35 or 70 mg once weekly (oral)

Risedronate 5 mg/day (oral) 5 mg/day (oral)
35 mg once weekly (oral) 35 mg once weekly (oral)
150 mg once monthly (oral) 150 mg once monthly (oral)

Ibandronate 2.5 mg/day (oral) 2.5 mg/day (oral)
150 mg once a month (oral) 150 mg once a month (oral)
2–3 mg every three months (IV)

Pamidronate Single doses should not
exceed 90 mg (IV)
Single doses should not exceed
90 mg (IV)

Zoledronic acid 5 mg every 12 months (IV) 5 mg every 12 months (IV)