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. Author manuscript; available in PMC: 2010 May 18.
Published in final edited form as: Free Radic Biol Med. 2008 Jul 31;45(9):1263–1270. doi: 10.1016/j.freeradbiomed.2008.07.020

Fig. 2.

Fig. 2

Linkages on Chromosome 3 suggest T1D and alloxan-induced diabetes may be controlled by different genes on this chromosome. (2A) The linkage on Chr. 3 mapped in a F2 population subjected to alloxan administration (Dotted line, peak χ2 =12.1, P=0.0024) does not overlap with previously reported linkage mapped in backcross population for type 1 diabetes. (2B) Effect plot of phenotype by microsatellite marker D3Nds6 shows NOD allele contributes to resistance while ALR allele contributes to susceptibility. Incidence of alloxan-induced Diabetes is on y-axis while genotype is on the x-axis (D = NOD; R = ALR).