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. Author manuscript; available in PMC: 2010 May 18.
Published in final edited form as: Leukemia. 2008 Sep 25;22(12):2142–2150. doi: 10.1038/leu.2008.251

Table 3. Overall five-year survival (OS) rates after relapse, by site and time to relapse.

5-year Survival Post Relapse Relapse Site
Isolated Marrow Relapse Concurrent Marrow Relapse Isolated CNS Relapse Isolated Testicular Relapse Other extramedullary +/-CNS Relapse
Time to relapse n Survival (%) SE n Survival (%) SE n Survival (%) SE n Survival (%) SE n Survival (%) SE
Early1 412 11.49 1.91 86 11.64 4.89 175 43.51 4.45 15 13.64 16.56 23 10.38 11.32
Intermediate1 324 18.42 3.09 54 39.79 9.31 180 67.99 4.53 35 52.20 11.41 17 50.47 25.12
Late1 387 43.46 5.23 124 60.34 8.29 54 78.25 8.85 54 59.96 15.49 21 85.15 14.67
Overall2 1123 24.1 2.1 264 39.4 5.0 409 58.7 3.2 104 58.0 8.2 61 55.9 9.9
1

p-value < 0.0001 compares survival rates by sites of relapse within each time period.

2

“Overall survival” refers to an unadjusted comparison of sites of relapse.