Skip to main content
. Author manuscript; available in PMC: 2010 May 18.
Published in final edited form as: Exp Gerontol. 2008 Jun 7;44(1-2):26–33. doi: 10.1016/j.exger.2008.05.014

Fig. 4.

Fig. 4

(A) Circulating Chromogranin A, Chromogranin B and Secretogranin II in 12 to 14 month-old female Snell dwarf mice. Plasma Chromogranin B and Secretogranin II were elevated in Snell dwarf mice by radioimmune assay. Bar graphs show results as means ± SEM. *Significantly different by nonparametric Student t-test where p < 0.05 and N = 15 mice per group for Chromogranin A and N = 5 mice per group for Chromogranin B and Secretogranin II. (B) Tissue Chromogranin B and Secretogranin II mRNA expression by Northern blot analysis in wild-type mice. Chromogranin B mRNA expression was detected in the pituitary and the adrenal glands while Secretogranin II mRNA expression was detected ubiquitously.