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. Author manuscript; available in PMC: 2010 May 18.
Published in final edited form as: Exp Gerontol. 2008 Jun 7;44(1-2):26–33. doi: 10.1016/j.exger.2008.05.014

Table 1.

Proteomics analysis of secreted proteins from the pituitary of Snell dwarf and control mice

Secreted pituitary proteins by proteomics analysis Control Snell dwarf
Growth hormone + ND
Prolactin + ND
ACTH + +
Chromogranin A + ++
Chromogranin A + ++
Secretogranin II + ++

Proteomics analysis confirmed that the pituitary of the Snell dwarf does not secrete GH or PRL and verified the secretion of ACTH, Chromogranin A, Chromogranin B and Secretogranin II secretion. LH, FSH and TSH secretion was not detected from Snell dwarf or control and pituitaries. The plus sign (+) indicates detected, two plus signs (++) indicate a 2-fold difference and ND indicates not detected. Pituitary secretion levels were compared using quantitative proteomics analysis software (Decyder MS).