Table 1.

Characteristics of samples with MSI status and BRAF genotyping

	BRAF Wild Type N = 1232	BRAF V600E N = 65	OR (95% C.I.)
Age (years)	70.3 (sd =11.5)	73.8 (sd = 11.1)	p=0.02
Range	21 - 99	45 - 93
Pack-years	33.7 (sd = 28.4)	36.4 (sd = 25.7)	p=0.68
Never smoked	693 (94.8)	38 (5.2)	0.85 (0.50 – 1.44)
Ever smoked	514 (95.5)	24 (4.5)	1.00
Ashkenazi Jewish	840 (94.2)	52 (5.8)	1.87 (1.01 – 3.47)
Non-Ashkenazi Jewish	392 (96.8)	13 (3.2)	1.00
Female	593 (93.4)	42 (6.6)	1.97 (1.17 – 3.31)
Male	639 (96.5)	23 (3.5)	1.00
HRT Use	22 (93.1)	2 (6.9)	0.94 (0.21 – 4.11)
No HRT Use	417 (92.7)	33 (7.3)	1.00
Aspirin/NSAID Use	326 (95.0)	17 (5.0)	1.00 (0.56 – 1.77)
No Aspirin/NSAID Use	863 (95.0)	45 (5.0)	1.00
1° Fam Hx of CRC	123 (94.6)	7 (5.4)	1.08 (0.48 – 2.42)
No Fam Hx of CRC	1103 (95.0)	58 (5.0)	1.00
MSI-high	106 (72.1)	41 (27.9)	18.1 (10.5 – 31.2)
MSS/MSI-Low	1126 (97.9)	24 (2.1)	1.00