Figure 34.
In vivo noninvasive PA images of the cerebral cortex acquired (A) before the injection, and (B) ~2 h after the final of PEGylated nanocages via tail vein. (C) A differential image (34B subtracted from 34A). (D) An open-skull photograph of the rat’s cerebral cortex. (E) Quantification of the PA signal enhancement after the injection as a function of time. (Reprinted with permission from ref 90. Copyright 2007 American Chemical Society.)