Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic of models. (A) An allosteric model in which release can occur from any occupancy state of a calcium sensor with five calcium binding sites. (B) Conventional model with three Ca2+ binding sites. In this model, release is restricted to the fully-occupied sensor and there is no additional cooperativity between binding sites. (C) Conventional two-site model.
