Table 2.
Model | α (M−1s−1) | β (s−1) | b | i (s−1) | f | Maximum rate (s−1) | χ2 |
---|---|---|---|---|---|---|---|
Five-site A | 1.3 × 108 | 145 | 1.0 | 1.5 × 10−3 | 9.2 | 100 | 52 |
Five-site A∗ | 4.6 × 107 | 146 | 1.0 | 1.5 × 10−3 | 21.1 | 6490 | 68 |
Five-site A∗† | 5.0 × 107 | 133 | 1.0 | 2.2 × 10−4 | 31.3 | 6448 | 76 |
Five-site A∗‡ | 4.2 × 107 | 148 | 1.0 | 5.0 × 10−3 | 16.7 | 5899 | 62 |
Five-site A§ | 1.5 × 108 | 161 | 1.0 | 1.4 × 10−4 | 14.7 | 100 | 60 |
Five-site A∗§ | 5.4 × 107 | 141 | 1.0 | 2.0 × 10−4 | 30.7 | 5369 | 77 |
Three-site C¶ | 2.3 × 107 | 54 | 2976 | 60 | |||
Three-site A | 1.6 × 107 | 73 | 1.0 | 1.4 × 10−3 | 168 | 6453 | 42 |
Three-site A∗‖ | 3.3 × 107 | 151 | 1.0 | 1.2 × 10−3 | 129 | 2631 | 61 |
Two-site C¶ | 7.1 × 106 | 14 | 3634 | 40 |
A, allosteric model; C, conventional model.
With weighted high point.
With spontaneous point at 2e−4.
With spontaneous point at 5e−3.
With spontaneous point at 50 nM Ca2+.
No weighted high point, no spontaneous point.
b not well-defined, selected to be near 1.