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. 2010 May 19;98(10):2102–2110. doi: 10.1016/j.bpj.2010.02.003

Table 2.

Best parameter sets

Model α (M−1s−1) β (s−1) b i (s−1) f Maximum rate (s−1) χ2
Five-site A 1.3 × 108 145 1.0 1.5 × 10−3 9.2 100 52
Five-site A 4.6 × 107 146 1.0 1.5 × 10−3 21.1 6490 68
Five-site A∗† 5.0 × 107 133 1.0 2.2 × 10−4 31.3 6448 76
Five-site A∗‡ 4.2 × 107 148 1.0 5.0 × 10−3 16.7 5899 62
Five-site A§ 1.5 × 108 161 1.0 1.4 × 10−4 14.7 100 60
Five-site A∗§ 5.4 × 107 141 1.0 2.0 × 10−4 30.7 5369 77
Three-site C 2.3 × 107 54 2976 60
Three-site A 1.6 × 107 73 1.0 1.4 × 10−3 168 6453 42
Three-site A∗‖ 3.3 × 107 151 1.0 1.2 × 10−3 129 2631 61
Two-site C 7.1 × 106 14 3634 40

A, allosteric model; C, conventional model.

With weighted high point.

With spontaneous point at 2e−4.

With spontaneous point at 5e−3.

§

With spontaneous point at 50 nM Ca2+.

No weighted high point, no spontaneous point.

b not well-defined, selected to be near 1.