Fig. 2.

Time course of survival rate of mice treated with PZ followed by LPS. PZ (100 mg/kg) was given to mice 1 or 2 h before LPS (40 mg/kg, i.p.) administration. Mice were monitored for survival over 96 h after LPS administration. PZ-2 h and PZ-1 h received PZ at 2 h and 1 h before LPS administration, respectively. ^#p<0.01 vs LPS alone at 96 h after LPS. ^$p<0.01 vs PZ-1 h at 96 h after LPS.