Fig. 3.

Inhibition by PZ of NO (A) and TNF-α (B) in plasma in mice injected with LPS. PZ (100 mg/kg) was given to mice 2 h before LPS (40 mg/kg, i.p.) administration. Blood samples were collected 6, 12, 18, 24 h after administration of LPS. Plasma NO and TNF-α concentrations were measured as described in Materials and Methods. Data points represent the means ± SE (n = 5). *p<0.01 vs LPS alone.