Fig. 4.

Effect of PZ on lung injury in mice 24 h after LPS administration. Mice were treated with PZ (100 mg/kg, p.o.) 2 h before LPS (40 mg/kg, i.p.) administration. Lung histopathological analysis was performed as described in Materials and Methods. Cont. (upper left): lung from control mouse; PZ (upper right): lung from mouse treated with PZ (100 mg/kg) alone; LPS (lower left): lung from mouse treated with LPS alone; PZ + LPS (lower right): lung from mouse treated with PZ at 2 h before LPS (H-E, magnification ×20).