Table 1.

Top 10 sequences from stage one with the highest fold specificities (Run 1)

Sequence	Sequence selection rank	Fold specificity rank	Approximate binding affinity rank		Position
				K∗	1	2	3	4	5	6	7	8	9	10	11	12	13
NCV-2	756	2	1	4.31 × 10−02	I	C	V	W	Q	D	W	G	R	N	N	C	W
NCV-10	809	10	2	3.30 × 10−02	V	C	V	W	Q	D	W	G	R	V	N	C	W
NCV-3	392	3	3	3.83 × 10−04	L	C	V	W	Q	D	W	G	Q	M	R	C	W
Variant E1	n/a	n/a	4	5.78 × 10−06	I	C	V	W	Q	D	W	G	A	H	R	C	T
NCV-5	684	5	5	4.10 × 10−07	W	C	V	W	Q	D	W	G	R	N	N	C	W
NCV-1	833	1	6	3.55 × 10−07	V	C	V	W	Q	D	W	G	Q	M	R	C	W
NCV-8	867	8	7	9.69 × 10−08	I	C	V	W	Q	D	W	G	Q	I	R	C	W
NCV-7	671	7	8	6.26 × 10−09	F	C	V	W	Q	D	W	G	Q	M	R	C	W
NCV-4	659	4	9	3.51 × 10−10	I	C	V	W	Q	D	W	G	Q	V	R	C	W
NCV-9	343	9	10	8.01 × 10−11	I	C	V	W	Q	D	W	G	Q	R	N	C	W
NCV-6	539	6	11	6.88 × 10−11	L	C	V	W	Q	D	W	G	Q	R	N	C	W
Native	n/a	n/a	12	4.27 × 10−12	I	C	V	V	Q	D	W	G	H	H	R	C	T

Mutations are indicated in boldface.