Table 1.

Secondary products of nicotine heterogeneous nitrosation by HONO.

	Product no.	Product name	Product structure	m/z	Yield %*
Gas-phase products	1	Formaldehyde		N/A†	< 0.05
	2	N-nitroso-pyrrolidine		100, 70, 68	< 0.05
	3	Methyl 3-pyridinecarboxylate (Methyl nicotinate)		137, 106, 78	< 0.05
	4	N-methylnicotinamide		136, 106, 78	0.1
Cellulose-sorbed species	5	4-(N-methyl-N-nitrosamino)-2-oxi-mino-1-(3-pyridyl)-1-butanone		219, 106, 130, 165, 78	< 0.05
	6	1-methyl-5-pyridin-3-yl-pyrrolidin-2-one (Cotinine)		176, 118, 98	0.3
	7	1-methyl-5-(3 pyridinyl) pyrazole		159, 158, 130, 118, 104, 78	0.8

^*Yields were determined on the basis of the ratio of peak areas of each product over nicotine.

^†Formaldehyde was determined by dinitrophenylhydrazine derivatization and HPLC analysis with UV detection.