Fig. 4.
Effect of Hrp48 knockdown on Notch protein and signaling is rescued by Sxl knockdown. Sxl levels are reduced (A, red; B, gray) by dpp-Gal4–driven UAS-RNAi-Sxl (A, marked by GFP, green). (C and D) Sxl knockdown on the A–P boundary (C, marked by GFP, green) results in elevated levels of N protein (C, red; D, gray). (E and F) hrp48 and Sxl simultaneous knockdown (E, marked by GFP, green) results in elevated levels of N protein on the D/V boundary (E, red; F, gray). (G and H) Sxl knockdown on the A/P boundary (G, marked by GFP, green) results in Dpn up-regulation on the D/V boundary (G, red; H, gray). hrp48 and Sxl simultaneous knockdown on the A/P boundary (I, marked by GFP, green) results in Dpn up-regulation on the D/V boundary (I, red; J, gray).