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No significant differences in the numbers of EC cells per gland (A, C) or the percentage of epithelial cells that were EC cells (B, D) were detected in the CC samples or in biopsies from individuals undergoing opiate therapy, as compared to healthy controls (p>0.05 for each group vs control). E: photomicrographs showing representative colonic glands that were used to quantify the EC cells in these preparations. n-values: A, 19, 11; B, 19, 11; C, 23, 25, 15; D, 23, 25, 15.
