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. Author manuscript; available in PMC: 2011 Feb 9.
Published in final edited form as: Curr Biol. 2010 Jan 28;20(3):271–277. doi: 10.1016/j.cub.2009.12.044

Figure 2. Dgcr8-Deficient Oocytes Can Be Fertilized and Produce Healthy Pups.

Figure 2

(A) Table summarizes the cross between Dgcr8delta/flox; Zp3-Cre or Dicerflox/flox; Zp3-Cre with wild-type males. For Dgcr8delta/flox; Zp3-Cre, each cross produces multiple litters, denoted by asterisk (*).

(B) Brood size from wild-type, Dgcr8delta/flox; Zp3-Cre (mutant), or Dgcr8delta/+ (het) mice. Each data point represents the number of pups per litter from wild-type (○), mutant (Δ), and het (◊) mothers. Brood size is reduced approximately 36% in the mutant compared to wild-type (p < 0.0001).