Table 2.
MISCAN-Colon model parameters as adjusted specifically to the trials.
| Parameter | Minnesota | Nottingham | Funen |
|---|---|---|---|
| Period | 1975-1981, 1987-1992 | 1981-1995* | 1985-2000† |
| Birth years population | 1895-1925 | 1906-1936 | 1910-1940 |
| RR for incidence compared to US population 1978 | 0.79 | 0.78 | 0.92 |
| RR for incidence non-attenders versus attenders | 1 | 1.3 | 1.4 |
| Stage distribution clinically diagnosed CRC | |||
| Dukes A | 25% | 13% | 12% |
| Dukes B | 34% | 35% | 38% |
| Dukes C | 23% | 31% | 24% |
| Dukes D | 19% | 21% | 26% |
| 10-years survival by stage | |||
| Dukes A | 91% | 87% | 87% |
| Dukes B | 75% | 69% | 69% |
| Dukes C | 44% | 43% | 43% |
| Dukes D | 1% | 4% | 4% |
| Screen interval | 1 year or 2 years | 2 years | 2 years |
| Attendance to | |||
| first screen | Age-dependent: 56-81% | 63% | 67% |
| repeat screen, if attended previously | 90% | 87% | 93% |
| repeat screen, if not attended previously | 42% | 14% | not re-invited: 0% |
| Specificity | Unrehydrated: 98% | 99% | 99% |
| Rehydrated: 90% |
RR: Relative risk
CRC: Colorectal Cancer
*
Results of first 5 rounds used
†
Results of first 8 rounds used