Table 2.
Validated structural variations.
| Type | Tumor source | Chromosome A | Breakpoint A | Orientation A | Chromosome B | Breakpoint B | Orientation B | Event size | Gene |
|---|---|---|---|---|---|---|---|---|---|
| Translocation | T,M,X | 1 | 245548334 | minus | 2 | 64855174 | plus | ZNF496 | |
| Translocation | T,M | 1 | 245548342 | Plus | 6 | 144243130 | plus | ZNF496, C6orf94 | |
| Translocation | T,M,X | 2 | 64855565 | Plus | 6 | 144243118 | minus | C6orf94 | |
| Translocation | T,M,X | 2 | 165126335 | plus | 16 | 4537866 | plus | GRB14 | |
| Translocation | T,M,X | 4 | 188855443 | plus | 9 | 139022260 | plus | ABCA2 | |
| Translocation | T,M,X | 12 | 10874022 | plus | 14 | 99382256 | minus | EML1 | |
| Translocation | T,M | 19 | 17188977 | minus | 3 | 188010735 | plus | USE1 | |
| Inversion | T,M,X | 1 | 35703682 | 1 | 35732148 | 28465 | KIAA0319L | ||
| Inversion | T,M,X | 1 | 95919529 | 1 | 95920940 | 1410 | |||
| Inversion | T,M,X | 1 | 204459097 | 1 | 204461297 | 2200 | |||
| Inversion | T,M,X | 1 | 204459547 | 1 | 204460581 | 1033 | |||
| Inversion | T,M,X | 4 | 177886041 | 4 | 177890171 | 4129 | VEGFC | ||
| Inversion | T,M,X | 19 | 17800861 | 19 | 17801858 | 996 | JAK3 | ||
| Deletion | M | 1 | 29389213 | 1 | 29416133 | 26919 | MECR | ||
| Deletion | T,M,X | 1 | 76496719 | 1 | 76496797 | 79 | ST6GALNAC3 | ||
| Deletion | T,M,X | 1 | 88291885 | 1 | 88292292 | 406 | |||
| Deletion | T,M,X | 2 | 18629189 | 2 | 19196656 | 567466 | NT5C1B | ||
| Deletion | T,M,X | 2 | 64853205 | 2 | 65010694 | 157488 | |||
| Deletion | T,M,X | 2 | 128745303 | 2 | 128898612 | 153308 | HS6ST1 | ||
| Deletion | T,M,X | 4 | 1203395 | 4 | 1265560 | 62164 | CTBP1 | ||
| Deletion | T,M,X | 4 | 135737399 | 4 | 135738718 | 1318 | |||
| Deletion | T,M,X | 4 | 147221480 | 4 | 147294628 | 73147 | AK057233 | ||
| Deletion | T,M,X | 4 | 153446894 | 4 | 153493357 | 46462 | FBXW7 | ||
| Deletion | T,M,X | 5 | 15572469 | 5 | 15572649 | 179 | FBXL7 | ||
| Deletion | T,M,X | 5 | 130743604 | 5 | 130743718 | 113 | CDC42SE2 | ||
| Deletion | T,M,X | 5 | 138131495 | 5 | 138669963 | 538467 | CTNNA1, LRRTM2, MATR3, SNORA74A, SIL1 | ||
| Deletion | T,M,X | 5 | 138141753 | 5 | 138657219 | 515465 | CTNNA1, LRRTM2, MATR3, SNORA74A, SIL1 | ||
| Deletion | T,M,X | 6 | 39689264 | 6 | 39689652 | 387 | KIF6 | ||
| Deletion | T,M,X | 7 | 999743 | 7 | 999984 | 240 | |||
| Deletion | T,M,X | 7 | 135419232 | 7 | 135419453 | 220 | |||
| Deletion | T,M,X | 8 | 32597100 | 8 | 32706664 | 109563 | NRG1 | ||
| Deletion | T,M,X | 8 | 116552846 | 8 | 116634665 | 81818 | TRPS1 | ||
| Deletion | T,M,X | 8 | 136595795 | 8 | 136596285 | 489 | KHDRBS3 | ||
| Deletion | T,M,X | 9 | 2746534 | 9 | 2746735 | 200 | |||
| Deletion | T,M,X | 10 | 77142378 | 10 | 77142881 | 502 | C10orf11 | ||
| Deletion | T,M,X | 11 | 115974418 | 11 | 115974688 | 269 | |||
| Deletion | T,M,X | 11 | 125479377 | 11 | 125479744 | 366 | |||
| Deletion | T,M,X | 17 | 24451601 | 17 | 24475255 | 23653 | MYO18A | ||
| Deletion | T,M,X | 17 | 73733446 | 17 | 73733547 | 100 | BIRC5 | ||
| Deletion | T,M,X | 18 | 46765510 | 18 | 46768017 | 2507 | ELAC1 | ||
| Deletion | T,M,X | X | 149511547 | X | 149548642 | 37094 | MTM1 |
*
T: primary tumor; M: metastasis; X: xenograft.