FIG. 3.
Average functional contrast in the visual cortex produced by the SLEPI and EPI sequences. The contrast is expressed as the percentage of signal enhancement during activation, compared to the baseline condition. The SLEPI contrast was obtained by application of a 500-Hz amplitude spin-locking pulse for a duration of 50 ms, followed by a standard EPI sequence with TE of 20, 30, or 50 ms. At TEs of 30 and 50 ms, the SLEPI sequence produced 55 and 24% higher functional contrast than the EPI sequence, respectively. Both increases were statistically significant (* P < 0.001).