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Substrate and product metabolite concentrations for reactions catalyzed by Eno1/2p, Fba1p, Pgk1p in the exponentially growing GCR2 mutant (green) and wild type (yellow) on glucose or on ethanol as sole carbon source. Eno1/2p, Fba1p, and Pgk1p exhibit lower enzyme activities in the mutant compared with the wild type (Uemura and Fraenkel, 1999) (data are found in Supplementary Table 4A).
