Figure 7.
Metabolite concentrations in S. cerevisiae strains with independently downregulated protein abundance. Protein abundances were modulated using yeast strains whose endogenous promotor was replaced by a Tet-controlled one. Blue background highlights the substrate metabolite for the perturbed enzyme abundance. Enzyme depicted in blue were modulated. G6P=glucose-6-P, F6P=fructose-6-P, FBP=fructose-bis-phosphate, DHAP=di-hydroxy-acetone-P, 2+3PG=2+3 P-glycerate, PEP=P-enol-pyruvate (data are found in Supplementary Table 4B).