Table 1. Baseline participant characteristics.
N | 142 | |
Female, n (%) | 87 (61%) | |
Age, median years (IQR) | 32 (28, 38) | |
Weight, median kg (IQR) | 45.5 (41, 51) | |
BMI, median kg/m2 (IQR) | 16.4 (15.4, 18.5) | |
CD4+ count, median cells/µL (IQR) | 34 (21, 47) | |
Hemoglobin, median g/dL (IQR) | 9.8 (8.8, 11.6) | |
Serum chemistries, median (IQR) | Reference Range [31] | |
Phosphate, mmol/L | 1.26 (1.03, 1.42) | 0.81–1.4 |
Potassium, mmol/L | 4.2 (3.7, 4.6) | 3.5–5.0 |
Chloride, mmol/L | 108 (103, 111) | 102–109 |
Bicarbonate, mmol/L | 29 (26, 31) | 22–30 |
BUN, mmol/L | 3.3 (2.4, 4.7) | 2.5–7.1 |
Creatinine, µmol/L | 71 (62, 88) | 44–106* |
Glucose (non-fasting), mmol/L | 3.9 (3.4, 4.8) | 4.2–6.1 |
Magnesium, mmol/L | 0.88 (0.79, 0.96) | 0.62–0.95 |
Albumin, g/L | 29.5 (23.9, 33.2) | 40–53* |
Ferritin, µg/L | 221 (59, 485) | 10–248* |
hsCRP, mg/L | 2.75 (1.1, 15.2) | 0.2–3.0 |
ART Regimen, n (%) | ||
AZT/3TC/EFV | 8 (5.6%) | |
AZT/3TC/NVP | 34 (23.9%) | |
d4T/3TC/EFV | 15 (10.6%) | |
d4T/3TC/NVP | 62 (43.7%) | |
TDF/FTC/EFV | 4 (2.8%) | |
TDF/FTC/NVP | 19 (13.4%) |
Abbreviations: ART, antiretroviral therapy; BMI, body mass index; BUN, blood urea nitrogen; hsCRP, high sensitivity C-reactive protein; IQR, interquartile range.
Among the 142 cases included in the multivariable analysis, values were missing for the following measurements: 8 (6%) baseline serum phosphate, 31 (22%) week one serum phosphate, 29 (20%) baseline hemoglobin (because either blood or assay reagents could not be obtained), 2 age (birth dates unknown), and one BMI (participant could not stand for height measurement).
*Normal creatinine range: females 44–80, males 53–106 µmol/L; normal albumin range: females 41–53, males 40–50 g/L; normal ferritin range: females 10–150, males 29–248 µg/L.