Table 1.
Recurrence rates and hazard ratios among clusters based on different elements
| Crude recurrence rate % [No.] | Hazard ratio [95% CI] | |
|---|---|---|
| WHL | P = 0.177 | |
| CLST A [61] | 4.9 [3] | 1.00 [ref.] |
| B [73] | 13.7 [10] | 2.97 [0.82-10.79] |
| C [22] | 22.7 [5] | 5.59 [1.33-23.41] |
| D [31] | 22.6 [7] | 5.85 [1.51-22.66] |
| ARC | P = 0.012 | |
| CLST A [73] | 3.9 [3] | 1.00 [ref.] |
| B [23] | 17.4 [4] | 5.53 [1.23-24.77] |
| C [67] | 16.4 [11] | 4.90 [1.37-17.57] |
| D [20] | 35.0 [7] | 11.34 [2.93-43.88] |
| CLL | P = 0.153 | |
| CLST A [84] | 11.9 [10] | 1.00 [ref.] |
| B [30] | 3.3 [1] | 0.27 [0.04- 2.13] |
| C [36] | 25.0 [9] | 2.57 [1.04- 6.33] |
| D [37] | 13.5 [5] | 1.34 [0.46- 3.92] |
| NCL | P = 0.260 | |
| CLST A [43] | 7.0 [3] | 1.00 [ref.] |
| B [48] | 18.8 [9] | 2.94 [0.80-10.85] |
| C [58] | 10.3 [6] | 1.51 [0.38- 6.03] |
| D [38] | 18.4 [7] | 3.20 [0.83-12.39] |
| CLL-NCL | P = 0.642 | |
| CLST A [46] | 10.9 [5] | 1.00 [ref.] |
| B [29] | 6.9 [2] | 0.66 [0.13- 3.38] |
| C [29] | 13.8 [4] | 1.53 [0.41- 5.71] |
| D [83] | 16.9 [14] | 1.66 [0.60- 4.61] |
| ARC-CLL | P = 0.138 | |
| CLST A [54] | 3.7 [2] | 1.00 [ref.] |
| B [70] | 15.7 [11] | 4.43 [0.98-19.98] |
| C [31] | 16.1 [5] | 4.65 [0.90-23.99] |
| D [32] | 21.9 [7] | 7.53 [1.56-36.28] |
| ARC-NCL | P = 0.044 | |
| CLST A [66] | 6.1 [4] | 1.00 [ref.] |
| B [26] | 3.8 [1] | 0.65 [0.07- 5.77] |
| C [76] | 19.7 [15] | 3.88 [1.29-11.69] |
| D [19] | 26.3 [5] | 6.10 [1.63-22.80] |
No., number of cases; P, P value, calculated with Fisher's exact test; CI, confidence interval; ref., reference; CLST, cluster; WHL, whole elements; ARC, architectural element; CLL, cell type and cytoplasmic elements; NCL, nuclear element.