Table 5.
Association between ARC-subCLST and personal characteristics
| Cluster | A1 | A2 | B | C1 | C2 | D |
|---|---|---|---|---|---|---|
| Stage I [191] | [36] | [42] | [23] | [41] | [25] | [20] |
| Age [mean ± SD Y/O] [67.8 ± 8.3 (45 to 85)] (Student's t test, no significant difference) | ||||||
| 69.2 ± 7.6 | 66.0 ± 8.0 | 66.7 ± 10.3 | 68.2 ± 8.4 | 69.9 ± 8.4 | 66.8 ± 8.1 | |
| Sex (Fisher's exact test, p = 0.0967) | ||||||
| Female [91] | 20 [55.6%] | 25 [59.5%] | 11 [47.8%] | 20 [48.8%] | 6 [24.0%] | 8 [40.0%] |
| Male [100] | 16 [44.4%] | 17 [40.5%] | 12 [52.2%] | 21 [51.2%] | 19 [76.0%] | 12 [60.0%] |
| Smoking History | ||||||
| Status (Fisher's exact test, p = 0.0012) | ||||||
| None [96] | 27 [75.0%] | 28 [66.7%] | 12 [52.2%] | 16 [40.0%] | 7 [29.2%] | 6 [33.3%] |
| Smoker [91] | 9 [25.0%] | 14 [33.3%] | 11 [47.8%] | 24 [60.0%] | 17 [70.8%] | 12 [66.7%] |
| N.A. [4] | 0 [–] | 0 [–] | 0 [–] | 1 [–] | 1 [–] | 2 [–] |
| Brinkmann index [mean ± SD] [454 ± 593 (0 to 3200)] (Student's t test, P < 0.0500: [A1,A2] vs [C2,D]) | ||||||
| 184 ± 333 | 316 ± 564 | 560 ± 708 | 479 ± 604 | 743 ± 586 | 682 ± 705 | |
| Stage IA [133] | [32] | [33] | [12] | [29] | [16] | [8] |
| Age [mean ± SD Y/O] [67.8 ± 7.7 (51 to 85)] (Student's t test, no significant difference) | ||||||
| 69.3 ± 7.1 | 66.5 ± 7.3 | 66.5 ± 8.8 | 68.2 ± 8.4 | 69.3 ± 7.6 | 70.0 ± 6.1 | |
| Sex (Fisher's exact test, p = 0.0356) | ||||||
| Female [66] | 18 [56.2%] | 21 [65.6%] | 6 [45.5%] | 16 [55.2%] | 4 [25.0%] | 1 [12.5%] |
| Male [67] | 14 [43.8%] | 12 [34.4%] | 6 [54.5%] | 13 [44.8%] | 12 [75.0%] | 7 [87.5%] |
| Smoking History | ||||||
| Status (Fisher's exact test, p = 0.0067) | ||||||
| None [71] | 24 [75.0%] | 23 [69.6%] | 5 [41.7%] | 12 [41.4%] | 5 [33.3%] | 2 [28.6%] |
| Smoker [60] | 8 [25.0%] | 10 [30.4%] | 7 [58.3%] | 17 [58.6%] | 10 [66.7%] | 5 [71.4%] |
| N.A. [2] | 0 [–] | 0 [–] | 0 [–] | 0 [–] | 1 [–] | 1 [–] |
| Brinkmann index [mean ± SD] [413 ± 574 (0 to 3200)] (Student's t test, P < 0.0500: [A1,A2] vs [C2,D]) | ||||||
| 186 ± 339 | 247 ± 436 | 670 ± 708 | 473 ± 665 | 732 ± 650 | 758 ± 754 | |
| Stage IB [58] | [4] | [9] | [11] | [12] | [9] | [12] |
| Age [mean ± SD Y/O] [67.9 ± 9.8 (45 to 84)] (Student's t test, no significant difference) | ||||||
| 68.0 ± 12.4 | 64.4 ± 10.1 | 66.8 ± 11.2 | 72.4 ± 6.8 | 71.3 ± 10.1 | 64.7 ± 8.7 | |
| Sex (Fisher's exact test, p = 0.8977) | ||||||
| Female [21] | 2 [50.0%] | 3 [33.3%] | 5 [54.5%] | 4 [33.3%] | 2 [22.2%] | 4 [33.3%] |
| Male [37] | 2 [50.0%] | 6 [66.7%] | 6 [45.5%] | 8 [66.7%] | 7 [77.8%] | 8 [66.7%] |
| Smoking History | ||||||
| Status (Fisher's exact test, p = 0.3097) | ||||||
| None [27] | 3 [75.0%] | 6 [66.7%] | 8 [72.7%] | 4 [36.4%] | 2 [22.2%] | 4 [36.4%] |
| Smoker [29] | 1 [25.0%] | 3 [33.3%] | 3 [27.3%] | 7 [63.6%] | 7 [77.8%] | 7 [63.6%] |
| N.A. [2] | 0 [–] | 0 [–] | 0 [–] | 1 [–] | 0 [–] | 1 [–] |
| Brinkmann index [mean ± SD] [544 ± 629 (0 to 2500)] (Student's t test, no significant difference) | ||||||
| 165 ± 330 | 531 ± 845 | 459 ± 723 | 496 ± 426 | 763 ± 496 | 734 ± 706 | |
ARC-subCLST, sub-clusters based on architectural element; SD, standard deviation; Y/O, year-old; None, non-smoker; N.A., not available.