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. 2010 May 17;2010:841343. doi: 10.1155/2010/841343

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Copyright © 2010 Carolyn M. Ecelbarger et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Mean kidney cytokine levels (all rats detectable) (a) higher level cytokines including: monocyte chemotactic protein-1 (MCP1), interleukin-2 (IL-2), interleukin-6 (IL-6), and interleukin-18 (IL-18); (b) lower level cytokines including: interleukin 1β(IL-1β),granulocyte macrophage colony-stimulating-factor (GM-CSF), growth regulated oncogene (GRO-KC), and interleukin-5 (IL-5) in whole kidney tissue homogenate from candesartan treated (CAN) or untreated (C) lean and obese rats at the end of 14 weeks of treatment (n = 8 per body type/treatment). ∗ indicates a significant difference (P < .05) from lean control mean and # from obese control mean, by unpaired t-test.