. Author manuscript; available in PMC: 2010 May 19.

Published in final edited form as: Mov Disord. 2008 Nov 15;23(15):2216–2223. doi: 10.1002/mds.22285

TABLE 2.

Comparison of raw GDS score among independent (one per family) carriers and noncarriers of genetic variants related to PD

Genetic variant^*	Percentage of carriers with depressive symptomatology (%)	Percentage of noncarriers with depressive symptomatology (%)	P-value
LRRK2 G2019S mutation	4.4	4.2	0.90
Any LRRK2 mutation	5.7	4.7	0.65
Homozygous PRKN mutation	9.3	10.2	0.82
Heterozygous PRKN	6.6	9.8	0.37
APOE4 polymorphism	20.0	26.5	0.18

Tests for association with genetic data were performed using only one individual per family (n = 537).