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(a) Influence of Zn-templated interfacial mutations in i1 on the conformations of Cu-mediated dimeric assemblies. (b) Backbone superposition of Cu2:RIDC-12 (grey) and a dimeric half of Zn4:RIDC-14 (orange) that contains i1. (c) Cu coordination environment in Cu2:RIDC-12, highlighting the open coordination sites occupied by two water molecules. The Glu81 sidechain from a crystallographic symmetry-related dimer is also shown.
