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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Nat Chem Biol. 2010 May 2;6(6):457–463. doi: 10.1038/nchembio.363

Equation 1. Definition of synergy ratios.

synergyratioobservedphenotypeexpectedphenotype=Φab1(1Φa)(1Φb)