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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Pharm Res. 2010 Jan 27;27(6):989–998. doi: 10.1007/s11095-010-0051-8

Fig. 4.

Fig. 4

Compounds shown to decrease Plk1 mRNA or protein levels. Treatment of cells with these compounds has been shown to decrease Plk1 mRNA and/or protein levels. The cause of this decrease in some instances is due to a G1 or S arrest, which would naturally decrease Plk1 levels due to Plk1 transcription and translation occurring mainly leading up to and during mitosis.