Figure 2.
Intracellular pH.
(A): 72 hours after myocardial infarction, the pH was significantly reduced in untreated (phosphate-buffered saline [PBS]) and control MSC-treated animals compared with sham, whereas it was normal in the Akt-MSC group. (B): At 2 weeks, the pH in the viable myocardium of the PBS and MSC animals was still significantly lower compared with both sham and Akt-MSC groups. *, p < .05 versus sham and Akt-MSC. Abbreviations: Akt-MSC, MSCs overexpressing Akt1; MSC, mesenchymal stem cells; PBS, phosphate-buffered saline.