Table 1.

Anatomical paremeters in sham, untreated (PBS), control MSC treated (MSC), and Akt-MSC treated animals at 72 hours and 2 weeks after myocardial infarction

	Sham (n=9)	PBS (n=7)	MSC (n=7)	Akt-MSC (n=9)
72 hours
Body weight (g)	211 ± 7	209 ± 6	216± 5	203 ± 2
Heart weight (mg)	628 ± 8	652 ± 2	620 ± 6	609 ± 3
LV weight (mg)	446 ± 5	449 ± 7	440 ± 5	429 ± 5
Infarcted tissue weight (mg)	-	89 ± 4	71 ± 4*	42 ± 5*#
2 weeks
Body weight (g)	215 ± 3	214 ± 5	213 ± 4	210 ± 3
Heart weight (mg)	693 ± 13	695 ± 11	695 ± 9	660 ± 13
LV weight (mg)	503 ± 13	498 ± 6	503 ± 10	466 ± 14
Infarcted tissue weight (mg)	-	96 ± 6	71 ± 5*	40 ± 7*#

Values expressed as average ± SE

^*p<0.05 vs PBS

^#p<0.05 vs MSC.

Abbreviations: Akt-MSC, MSCs overexpressing Akt1; LV, left ventricular; MSC, mesenchymal stem cells; PBS, phosphate-buffered saline.