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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Cancer Gene Ther. 2010 Feb 5;17(6):375–386. doi: 10.1038/cgt.2010.1

Table I. Promoter/Enhancer elements used in the construction of adenoviral vectors.

Promoter Gene source and promoter regions Organism Binding site sequence References
SRa Chimera of SV40 early promoter (-286,+63) + HTLV-1 LTR (+1,+267) Viral 16
SURV Survivin promoter (-938,+39) Human 18
RSV Rous Sarcoma Virus LTR Viral 19
CMV Cytomegalovirus immediate early promoter (-804,+7) Viral 13
C3/CMV Chimera of murine complement C3 enhancer (-386,-25), mJunB1 binding site (x2) and CMV i.e. promoter (-121,+5) Mouse/Viral 5′-CGGGAAGTTC-3′ 14
Fbe8TK FoxO binding element (x8) + HSV thymidine kinase promoter (-112,+57) Human/Viral 5′-CTCCAATAAACAAGCCTCGA-3′ 25
mEpo Erythropoietin promoter (-410,+1) + 3′ enhancer element Mouse NT_039315.7 np#212282-212214 21, 22
SOD2 Superoxide Dismutase 2 promoter (-1452,+40) Mouse 20, 22
CAIX Carbonic Anhydrase IX promoter (-440,+31) Human 21
PAI-1 Plasminogen Activator Inhibitor-1 (-787,+65) Human 41
Hy3PAI HIF-1a Response Element from hEpo (x3) + Plasminogen Activator Inhibitor-1 promoter (-809,+26) Human 5′-GCCCTACGTGCTGTCTCACACAGCCTGTCTGACCTCT CGACCTACCGGCC-3′ 41, 42
Hre3TK HIF-1a Response Element from Epo (x3) + HSV Thymidine Kinase promoter (-112,+57) Human/Viral 5′-AGCCCTACGTGCTGTCTCACACAGCCTGTCTGACCTC TCGACCTACCGGCCGTTCGA-3′ 23, 24
Myo2.0 Myoglobin promoter (-2038,+7) Human 43