Table 2.
Association of mismatch repair protein expression with clinical and pathological characteristics
| Characteristic | Mismatch repair protein expression |
p-value | |
|---|---|---|---|
| negative | positive | ||
| Sex, n (%) | |||
| Men | 3 (42.9) | 67 (42.7) | 0.99a |
| Women | 4 (57.1) | 90 (57.3) | |
| Age at diagnosis (years), mean ± SD (95% confidence interval) | 59.9 ± 21.7 (39.8–79.9) | 62.85 ± 13.2 (60.8–64.9) | 0.57b |
| Personal history of any other cancer, n (%) | |||
| No | 6 (85.7) | 142 (90.4) | 0.68a |
| Yes | 1 (14.3) | 15 (9.6) | |
| Family history of any cancer if available, n(%) | |||
| No | 1 (25) | 50 (42.4) | 0.49a |
| Yes | 3 (75) | 68 (57.6) | |
| Not available | 42 | ||
| Tumor location if available, n (%) | |||
| Proximal | 5 (71.4) | 42 (27.6) | 0.024c |
| Distal | 2 (28.6) | 110 (72.4) | |
| Not available | 5 | ||
| Tumor size (cm), mean ± SD (95% CI) | 6.0 ± 2.0 (3.9–8.1) | 4.4 ± 2.33 (4.0–4.8) | 0.09b |
| Tumor histological differentiation, n (%) | |||
| Well / moderate | 2 (28.6) | 131 (83.4) | 0.001a |
| Poor | 5 (71.4) | 26 (16.6) | |
| Tumor stage, n (%) | |||
| I | 0 (0) | 9 (5.7) | 0.63a |
| II | 3 (42.9) | 63 (40.1) | |
| III | 3 (42.9) | 43 (27.4) | |
| IV | 1 (14.2) | 13 (8.3) | |
| Not available | 0 (0) | 29 (18.5) | |
| Tumor recurrence, n (%) | |||
| No | 7 (100) | 142 (90.4) | 0.39a |
| Yes | 0 (0) | 15 (9.6) | |
SD = Standard deviation, cm = Centimeters
p-value determined by
a
Pearson Χ2 test,
b
two-sample t test with equal variances, and
c
Fisher’s exact test