Figure 4. IKKβ regulates anchorage-independent growth in ovarian cancer cell lines.
Six ovarian cancer cell lines were treated with small molecule IKKβ inhibitors and assayed for their ability to grow in soft agar. The same profile of sensitivity was apparent in cells treated with (A) ML120b, (B) IKKβ inhibitor IV, or (C) IKKβ inhibitor VI.