Table II.
Association between infant leukemia and latent class measure of infertility.
| Controls |
Cases |
ORa | 95% CI | MLL+ |
ORa | 95% CI | MLL− |
ORa | 95% CI | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | (%) | n | (%) | n | (%) | n | (%) | ||||||||
| Combined leukemia | Latent class infertility | ||||||||||||||
| No | 266 | (82.1) | 372 | (84.0) | Ref | 192 | (84.2) | Ref | 121 | (82.9) | Ref | ||||
| Yes | 58 | (17.9) | 71 | (16.0) | 0.97 | 0.63–1.48 | 36 | (15.8) | 0.98 | 0.58–1.65 | 25 | (17.1) | 1.13 | 0.63–2.01 | |
| ALL | Latent class infertility | ||||||||||||||
| No | 266 | (82.1) | 217 | (82.2) | Ref | 131 | (83.4) | Ref | 62 | (80.5) | Ref | ||||
| Yes | 58 | (17.9) | 47 | (17.8) | 1.27 | 0.79–2.05 | 26 | (16.6) | 1.20 | 0.68–2.13 | 15 | (19.5) | 1.40 | 0.69–2.85 | |
| AML | Latent class infertility | ||||||||||||||
| No | 266 | (82.1) | 149 | (86.6) | Ref | 59 | (86.8) | Ref | 56 | (84.8) | Ref | ||||
| Yes | 58 | (17.9) | 23 | (13.4) | 0.65 | 0.36–1.18 | 9 | (13.2) | 0.70 | 0.29–1.67 | 10 | (15.2) | 0.89 | 0.40–2.02 | |
ALL, acute lymphoblastic leukaemia; AML, acute myeloid leukaemia; MLL, mixed lineage leukaemia.
aLogistic regression models were adjusted for year of birth (quartiles), maternal age (continuous), maternal education, maternal race, smoking during pregnancy, household income, gestational age and birthweight.