Whole brain activation showing significantly greater activation for women compared to men during the high-calorie > low-calorie food image contrast. A) Women showed significantly greater activation than men within the middle frontal gyrus (MFG), as evident in the axial (left), sagittal (middle), and coronal planes (right). B) Women showed significantly greater activation than men within the inferior lateral orbitofrontal gyrus (Inf Lat OFC), medial orbitofrontal cortex (Med OFC), and middle/posterior cingulate gyrus.