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. Author manuscript; available in PMC: 2010 May 19.
Published in final edited form as: Anat Rec (Hoboken). 2009 Jul;292(7):1045–1061. doi: 10.1002/ar.20921

Figure 9. Neonatal Exposure to Hyperoxia Results in Adult Airway Hyperresponsiveness which was Attenuated with ROSI treatment.

Figure 9

Measurements of airway resistance (A) and dynamic compliance (B) in response to methacholine (MCh) challenge were performed on mice having been exposed to RA, RA+ROSI, Hyperoxia or HE+ROSI on P55. Mice exposed to hyperoxia had significantly increased airway hypreresponsiveness (AHR) than the RA controls and HE+ROSI groups. In both cases the HE+ROSI group was not significantly different from the RA control groups.