Table 1.
Nucleotide polymorphisms and consequent amino acid substitutions within the BKV subtyping region, used by Jin et al. (1993) to classify the different BKV isolates into four viral subtypes. Non-discriminatory nucleotides have been omitted for simplicity.
| BKV subtype (viral strain) | Nucleotides at indicated positionsa | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1744–46 | 1747 | 1760 | 1765–67 | 1768–70 | 1775 | 1784 | 1787 | 1792–94 | 1809 | 1811 | |
| I (DUN) | G.A | A | T | .TA | AAG | G | A | A | AGC | G | G |
| II (SB) | G.T | A | A | .TA | AAG | C | A | C | GAC | C | A |
| III (AS) | G.T | A | A | .AG | CAC | G | A | C | GAG | C | G |
| IV (IV) | A.T | G | A | .TA | AGA | C | C | C | GAG | C | G |
| Amino acids at indicated positions | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 61 | 62 | 66 | 68 | 69 | 71 | 74 | 75 | 77 | 82 | 83 | |
| I (DUN) | Glu | Asn | Phe | Leu | Lys | Ser | Asn | Asp | Ser | Glu | Arg |
| II (SB) | Asp | Asn | Tyr | Leu | Lys | Thr | Asn | Ala | Asp | Asp | Lys |
| III (AS) | Asp | Asn | Tyr | Gln | His | Ser | Asn | Ala | Glu | Asp | Arg |
| IV (IV) | Asn | Asp | Tyr | Leu | Arg | Thr | Thr | Ala | Glu | Asp | Arg |
a
Numbering according to Seif et al., 1979