Skip to main content
. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: J Infect Dis. 2010 Jun 1;201(11):1708–1717. doi: 10.1086/652496

Figure 4.

Figure 4

In vitro effects of activated transfected killer (ATAK) cells. A, Unactivated transfected HL-60 cells were compared with ATAK cells for their ability to kill Candida albicans in vitro. Results are from 3 experiments, each done in triplicate. Medians and interquartile ranges are shown. *P< .01 vs. control. B, Viability of unactivated (HL-60) or activated (ATAK) cells transfected with herpes simplex virus (HSV) thymidine kinase (TK) and cultured for 4 days in normal media or media plus 25 μmol/L ganciclovir (GCV). C, Viability of ATAK cells after irradiation with a mean dose (± standard deviation) of 2182 ± 241 rads cultured for 8 days in the presence or absence of varying concentrations of GCV. Medians and interquartile ranges are shown. Results are from 3 experiments combined. D, HL-60 cells that were untransfected; transfected with green fluorescent protein (GFP), thymidine kinase (TK), or hRluc alone; or transfected dually with GFP-hRluc or TK-hRluc. Cells were activated with dimethyl sulfamethoxazole and retinoic acid, and luminescence was imaged in tissue culture plate using an in vitro imaging system (Caliper Life Sciences) and quantified by a luminometer.